Abstract
The exosome is a protein complex formed by eleven subunits, which is present in archaea and eukaryotes, has exoribonucleolytic activity in the 3'-5' direction, and is involved in processing and/or degradation of all kinds of RNA. Our laboratory has been working on the functional and structural characterization of the archaeal and yeast exosomes, and has shown the structure of the Pyrococc…