CV Lattes
Universidade de São Paulo (USP). Faculdade de Medicina (FM) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Post-doctoral fellow at University of Washington. Ph.D in Science from the Medical School - University of Sao Paulo, developed research in lipids metabolism disorders and atherosclerosis development and adipose tissue-related inflammation lead by factors such as metabolic syndrome, hyperglycemia, hypertension and chronic kidney disease, associated to the effects of advanced glycation end products. (Source: Lattes Curriculum)
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Advanced glycation end products (AGE) are independently associated with the development of atherosclerosis. AGE reduce cholesterol efflux from macrophages and enhance the uptake of LDL, leading to lipid accumulation in these cells. Furthermore, AGE stimulate both angiotesinogen and angiotensin II receptor (AT-1) expression and share, together with AT-1, intracellular signalling pathways …
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