Abstract
Crotoxin (CTX), the major toxin of Crotalus durissus terrificus venom induces anti-inflammatory and immunomodulatory effects. Despite the inhibitory actions on neutrophil migration and the phagocytic activity of these cells, this toxin does not alter the microbicidal activity of neutrophils activated by PMA. On the other hand, CTX enhances the generation of reactive oxygen intermediates a…