Abstract
Thyroid hormones act in all organs and metabolic pathways of the human body. They exert their functions through binding to TR and TR-± and ² receptors. T3 and TRIAC, which have a greater affinity for TR-² than T4, appear to stimulate epidermal proliferation, dermal thickening, and hair growth when used topically. In this context, natural and synthetic TR-² ligands have emerged as a promis…