Abstract
The focal and segmental glomerulosclerosis (FSGS) is a major cause chronic kidney disease (CKD) in the world. FSGS is characterized by massive proteinuria associated with involvement of epithelial cells (podocytes). Experimental models classical FSGS can be induced by administration of chemotherapeutic drugs such as adriamycin (ADM). The model of nephropathy induced by ADM mimics the clas…