Abstract
Pluripotent stem cells (PSC) have ability of self-renewal and differentiate into all cell types of the embryo. The pluripotency can be demonstrated by several experiments in vitro and in vivo such as expression of pluripotent markers (oct3 / 4 and NANOG), differentiation capacity in all cell types of the three germ layers and chimera formation. PSC are isolated in vitro from early stages…