CV Lattes
Universidade de São Paulo (USP). Faculdade de Medicina de Ribeirão Preto (FMRP) (Institutional affiliation from the last research proposal) Birthplace: Brazil
bachelor's at Ciências Biológicas from Universidade Estadual do Norte do Paraná, Campus Luiz Meneghel (2008) and master's at Imunologia Básica e Aplicada (conceito CAPES 7) from Faculdade de Medicina de Ribeirão Preto - USP (2012). Has experience in Immunology, focusing on Immunology, acting on the following subjects: toxoplasma gondii, microneme proteins, toll-like receptors 2 and 4, macrophages and germinação. (Source: Lattes Curriculum)
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To adhere to host cells Toxoplasma gondii uses microneme proteins (MICs), making their adhesive domains essential for the parasite virulence. MICs can be found associated with each other on the tachyzoite surface, like the complex TgMIC1/MIC4/MIC6. We have previously demonstrated that pure TgMIC1/MIC4 subcomplex, obtained through adsortion to immobilized lactose, can stimulate macrophages…
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