Abstract
Marfan syndrome (MS) (MIM=15470) is a conective tissue disease of autossomal dominant inheritance, with clinical variability intra and inter familial, and no predilection for race or sex, that shows a prevalence of 1/10.000 individuals. Aproximately 30% of the cases are sporadical and the remain inherited the clinical manifestations are concetrated in three main systems: skeletal, cardiov…