Abstract
Stress inducible protein 1 is known as a co-chaperone capable of modulating the activity of heat shock proteins (Hsps) 70-90 kDa. It's cell distribution indicates that this protein can form multiprotein complexes in the nucleus, cytoplasm, and extracellular milieu, with different biological activities. In their soluble form interacts with the cellular prion protein (PrPC), a plasma membra…