CV Lattes
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Universidade Federal de São Paulo (UNIFESP). Campus Diadema. Instituto de Ciências Ambientais, Químicas e Farmacêuticas (ICAQF) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduation at Licenciatura em Química from Universidade Presbiteriana Mackenzie (1997), graduation at Bacharel Em Quimica from Universidade Presbiteriana Mackenzie (1998) and doctorate at Biochemistry from Universidade de São Paulo (2003). He is currently full professor at Universidade Federal de São Paulo. Has experience in Parasitology, focusing on Parasite Protozoology, acting on the following subjects: trypanosoma cruzi, doença de chagas, metabolismo energético, transportadores and gp85/trans-sialidase. (Source: Lattes Curriculum)
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The genus Giardia include diplomonadida parasites of global importance that causes diarrhea in humans (Giardia lamblia specie) and other vertebrates. In vitro two-dimensional (2D) cell cultures for studying Giardia infections that have physiological relevance are rare and the use of animal models are limited to ethical constraints. For these reasons, 2D cell monolayers are been replaced b…
Giardia lamblia and Cryptosporidium spp. are important enteric protozoa parasite responsible for Giardiasis and Cryptosporidiosis, respectively. Both are diarrheic diseases affecting humans and animais worldwide. Giardia causes disease without invading adjacent tissues and secreting toxins. Several mechanisms have been proposed to be importanf for induction of symptoms during a Giardia in…
The network of microtubules (MTs) and microfilaments (F-actin) are crucial cytoskeletal structures responsible for the maintenance of the cell morphology, proliferation, migration and differentiation. These filaments regulate the dynamic a number of cellular processes and are reorganized, for example, during cell mitosis to form rounded cells with increased cortical rigidity. The cytoskel…
(Only some records are available in English at this moment)
The use of living beings for pharmacokinetic tests is very importat to stipulatesafety of use and observation of effects in complex organisms. Animal modelsare also used in basic research to understand the pathogenesis of certaindiseases and organ function at the cellular level. Currently, with the advent of techniquesof cell biology, it was possible to create in vitro cultures morphologi…
The gastrointestinal tract is covered by a monolayer of epithelial cells that act as a semipermeable barrier. The function of this barrier is due to the presence of a multiprotein complex that allows the selective passage of ions, water and other molecules through the epithelium. This complex is formed by three types of cellular junctions, with the tight junctions being the main factors r…
The intestinal parasite Giardia lamblia, etiological agent of giardiasis, affects every year millions people all over the world. Most highlighted symptoms of giardiasis are diarrhea, flatulence, malabsorption syndrome and intense abdominal pain. The infection by Giardia lamblia starts with the ingestion of cysts (resistant and infective form of the parasite). Once in the stomach, the acid…
SUMOylation is a post-translational modification of proteins characterized by the addition of an ubiquitin-like protein in lysine residues of the substrate. In this study, SUMOylation pathway in Giardia lamblia, a protozoan parasite which colonizes mammals small intestines, will be studied. Cellular biology aspects of the parasite, of its life cycle and its interaction with its host will …
(Only some records are available in English at this moment)
| 6 / 6 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 6 / 4 | Completed scholarships in Brazil |
| 13 / 11 | All research grants and scholarships |
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