Abstract
Nocturnin (carboncataboliterepression 4-like - CCRN4L) is a deadenylase that regulates target gene expression by both increasing mRNA degradation and silencing of mRNA translation. Nocturnin is a circadian-regulated protein expressed in several tissues, particularly in the liver. Noc-/- mice show alteration in the rhythmic expression of several key regulator of lipid metabolism, such as S…