Abstract
Sickle cell anemia occurred due to a single mutation in beta globin gene and its is characterized by vaso-occlusion episodes (pain crises), vasculopathy, acute thoracic syndrome, ischemic stroke, etc. Strokes are due to macro vascular lesions with vaso-occlusion and had an incidence of 10 to 25%. At present time, to prevent recurrent stroke in pediatric patients, chronic transfusion is us…