Abstract
Molecular dynamics (MD) simulations will be performed to describe intermediate states of amyloid $\beta$-peptides (A$\beta$) with 40 residues (A$\beta_{40}$), 42 residues (A$\beta_{42}$), and a set of peptides obtained by local mutations in the A$\beta$ sequences. A$\beta$ peptides and their mutant variants play a central role in Alzheimer's disease and present different toxicity and aggr…