CV Lattes
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ORCID
Universidade Federal de São Paulo (UNIFESP). Campus Diadema. Instituto de Ciências Ambientais, Químicas e Farmacêuticas (ICAQF) (Institutional affiliation from the last research proposal) Birthplace: Brazil
BSc in Chemistry (1998) - State University of Londrina; MSc in Organic Chemistry (2001) - University of São Paulo - Advisor: Prof. Dr. Antonia T. Amaral; PhD in Organic Chemistry (2005) - University of São Paulo - Advisor: Prof. Dr. João V. Comasseto; Postdoctoral studies in Organic Synthesis (2006) - Iowa State University (USA) - Supervisor: Prof. Dr. Richard C. Larock; Head of Research and Development Laboratory - Formil Química Ltda (2007); Postdoctoral studies in Organic Synthesis (2008) - University of São Paulo - Supervisor: Prof. Dr. João V. Comasseto; Adjunct Professor - Federal University of Grande Dourados (2011); Associate Professor - Federal University of São Paulo - Diadema Campus (current institution); Director of the Organic Chemistry Division of the Brazilian Chemical Society (2018-2020); Researcher at the Centre for Global Health at Unifesp (CSG-Unifesp) (since 2022); Area of Expertise: Organic Chemistry (Organic Synthesis); Research Lines: 1) Organometallic catalysis; 2) Chemistry of benzyne and derivatives, and 3) Total synthesis of natural products and bioactive substances. (Source: Lattes Curriculum)
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Benzyne and its derivatives, named arynes, are highly reactive intermediates, which have relatively low LUMO energies and considerable electrophilic character, successfully used in the synthesis of natural products and preparations of functional materials. In this context, we intend to explore the chemistry of benzyne by the synthesis of water-soluble anthraquinones, through 2-(trimethyls…
Benzyne and its derivatives, called arynes, are highly reactive intermediates, with recognized importance in organic chemistry, successfully employed in syntheses of natural products and preparations of functional materials. In this sense, TMS-aryl trifluoromethanesulfonates have emerged as an important alternative for the formation of benzyne and arynes under mild reaction conditions, en…
The benzyne chemistry has found applications in organic chemistry, including total syntheses of natural products and preparations of functional materials. In this sense, 2-(trimethylsilyl)aryl trifluoromethanesulfonates emerge as an important alternative for the formation of benzyne and derivatives, under mild reaction conditions, enlarging the scope of benzyne chemistry applications in p…
The benzyne chemistry has found applications in organic chemistry, including total syntheses of natural products and preparations of functional materials. In this sense, 2-(trimethylsilyl)aryl trifluoromethanesulfonates appear as an important alternative for the formation of benzyne and derivatives, under mild reaction conditions, enlarging the scope of benzyne chemistry application in pr…
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Benzyne chemistry has found applications in organic chemistry, including total syntheses of natural products and preparations of functional materials. In this sense, 2-(trimethylsilyl)aryl trifluoromethanesulfonates appear as an important alternative for the formation of benzyne and derivatives under mild reaction conditions. Accordingly, we intend to develop alternative routes for the sy…
Due to the considerable importance of 2-(trimethylsilyl)aryl triflates in the current context of the benzyne chemistry, we intend to develop the convergent total synthesis of the aporphine alkaloid (R)-(-)-apomorphine, which is used as medicine in the therapy of Parkinson's disease and in the treatment of erectile dysfunction, employing approach that presents in the key step [4+2] cycload…
Due to the considerable importance of 2-(trimethylsilyl)aryl triflates in the current context of the benzyne chemistry, we intend to prepare iodinated 2-(trimethylsilyl)aryl triflates with unprecedented structures, envisioning the employment of such aryne precursors in Suzuki coupling reaction, followed by intramolecular cyclizations, producing carbazoles and dibenzofurans, which constitu…
| 1 / 1 | Ongoing grants |
| 5 / 5 | Completed research grants |
| 5 / 3 | Completed scholarships in Brazil |
| 11 / 9 | All research grants and scholarships |
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