Lucio Holanda Gondim de Freitas Junior

• São Paulo School of Advanced Science on Neglected Diseases Drug Discovery: Focus on Kinetoplastids (SPSAS-ND3) | Campinas - SP, AO.R.ESPCA
• Plasmodium berghei as a model for studying antigenic variation in malaria, AP.JP

• Abstract

  Chikungunya virus (CHIKV), an arbovirus belonging to the family Togavirideae, is the causative agent of Chikungunya Fever. Chikungunya is re-emerging as a significant public health problem and was responsible for a massive outbreak in Asia in 2006, and since then regular epidemics have occurred worldwide. A main concern with CHKV is that it is transmitted by the ubiquitous urban mosquit...

  A cell-based high throughput screening strategy for Chikungunya drug discovery, BP.DD

• Abstract

  Two billion people are estimated to be affected by parasitic infectious disease according to the World Health Organization. The most serious concern for the future is the emergence of resistance to all anthelmintic currently used to treat infection by parasitic worms. Caenorhabditis elegans is a free-living nematode naturally found in soil that has become a model organism for investigat...

  A whole animal Caenorhabditis elegans high content screening strategy as a surrogate model for drug discovery against worms of medical and veterinary importance, BP.DD

• Abstract

  Malaria is the parasitic disease that most affects populations in the world, causing high morbity and mortality, besides great financial costs to the endemic country. Essential strategy for the disease control, chemotherapy is hampered by the widespread resistance of parasites to the antimalarials that target their asexual forms. With the exception of primaquine, which causes severe adv...

  Identification of antimalarials with anti-gametocytocidal potentials, BP.PD

(Only some records are available in English at this moment)