Lucio Holanda Gondim de Freitas Junior
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Secretaria da Saúde (São Paulo - Estado). Instituto Butantan (Institutional affiliation for the last research proposal) Birthplace: Brazil
Lucio Holanda Gondim de Freitas Junior in research grants and scholarships supported by FAPESP.
| News published in Agência FAPESP Newsletter about the researcher |
| Hepatitis C drug rids organism of chikungunya and yellow fever viruses |
| Brazil must strengthen medicinal chemistry to achieve progress in drug discovery |
- A cell-based high throughput screening strategy for Chikungunya drug discovery, BP.DD
Abstract
Chikungunya virus (CHIKV), an arbovirus belonging to the family Togavirideae, is the causative agent of Chikungunya Fever. Chikungunya is re-emerging as a significant public health problem and was responsible for a massive outbreak in Asia in 2006, and since then regular epidemics have occurred worldwide. A main concern with CHKV is that it is transmitted by the ubiquitous urban mosquit...
- A whole animal Caenorhabditis elegans high content screening strategy as a surrogate model for drug discovery against worms of medical and veterinary importance, BP.DD
Abstract
Two billion people are estimated to be affected by parasitic infectious disease according to the World Health Organization. The most serious concern for the future is the emergence of resistance to all anthelmintic currently used to treat infection by parasitic worms. Caenorhabditis elegans is a free-living nematode naturally found in soil that has become a model organism for investigat...
- Identification of antimalarials with anti-gametocytocidal potentials, BP.PD
Abstract
Malaria is the parasitic disease that most affects populations in the world, causing high morbity and mortality, besides great financial costs to the endemic country. Essential strategy for the disease control, chemotherapy is hampered by the widespread resistance of parasites to the antimalarials that target their asexual forms. With the exception of primaquine, which causes severe adv...
(Only some records are available in English at this moment)
| 2 / 1 | Completed research grants |
| 8 / 6 | Completed scholarships in Brazil |
| 1 / 0 | Completed scholarships abroad |
| 11 / 7 | All research grants and scholarships |
| Associated processes | |
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
| Publications | 2 |
| Citations | 10 |
| Cit./Article | 5.0 |
| Data from Web of Science | |
CONTRERAS-DOMINGUEZ, MONICA; MORAES, CAROLINA BORSOI; DORVAL, THIERRY; GENOVESIO, AUGUSTE; DOSSIN, FERNANDO DE MACEDO; FREITAS-JUNIOR, LUCIO H.. A modified fluorescence in situ hybridization protocol for Plasmodium falciparum greatly improves nuclear architecture conservation. Molecular and Biochemical Parasitology, v. 173, n. 1, p. 48-52, SEP 2010. Web of Science Citations: 2.
ALCANTARA, LAURA M.; FERREIRA, THALITA C. S.; GADELHA, FERNANDA R.; MIGUEL, DANILO C.. Challenges in drug discovery targeting TriTryp diseases with an emphasis on leishmaniasis. INTERNATIONAL JOURNAL FOR PARASITOLOGY-DRUGS AND DRUG RESISTANCE, v. 8, n. 3, p. 430-439, DEC 2018. Web of Science Citations: 8. (15/24595-9, 14/21129-4, 15/10436-6)
FREITAS‚ L.H.G.; PORTO‚ R.M.; PIRRIT‚ L.A.; SCHENKMAN‚ S.; SCHERF‚ A.; OTHERS. Identification of the telomere in Trypanosoma cruzi reveals highly heterogeneous telomere lengths in different parasite strains. Nucleic Acids Research, v. 27, n. 12, p. 2451-2456, 1999.