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Ariel Mariano Silber

CV Lattes GoogleMyCitations

Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB)  (Institutional affiliation for the last research proposal)
Birthplace: Argentina

graduation at Licenciatura en Ciencias Biológicas from Universidad de Buenos Aires (1992) and doctorate at Doutorado Pela Universidade de Buenos Aires from Universidad de Buenos Aires (2000). He is currently full professor at Universidade de São Paulo. Has experience in Biochemistry, focusing on Biochemistry, acting on the following subjects: trypanosoma cruzi, calflagin, diagnosis, ca2+ binding proteins and diagnóstico. (Source: Lattes Curriculum)

Research grants
Scholarships in Brazil
Scholarships abroad
FAPESP support in numbers*
*Updated May 18, 2019
Most frequent collaborators in research granted by FAPESP
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Use this Research Supported by FAPESP (BV/FAPESP) channel only to send messages referring to FAPESP-funded scientific projects.





Keywords used by the researcher
Scientific publications resulting from Research Grants and Scholarships under the grantee's responsibility (35)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

Data from Web of Science

GRAZU, V.; SILBER, A. M.; MOROS, M.; ASIN, L.; TORRES, T. E.; MARQUINA, C.; IBARRA, M. R.; GOYA, G. F.. Application of magnetically induced hyperthermia in the model protozoan Crithidia fasciculata as a potential therapy against parasitic infections. INTERNATIONAL JOURNAL OF NANOMEDICINE, v. 7, p. 5351-5360, . Web of Science Citations: 16.

PAES, LISVANE SILVA; MANTILLA, BRIAN SUAREZ; ZIMBRES, FLAVIA MENEZES; FURUSHO PRAL, ELISABETH MIEKO; DE MELO, PATRICIA DIOGO; TAHARA, ERICH B.; KOWALTOWSKI, ALICIA J.; ELIAS, MARIA CAROLINA; SILBER, ARIEL MARIANO. Proline Dehydrogenase Regulates Redox State and Respiratory Metabolism in Trypanosoma cruzi. PLoS One, v. 8, n. 7, . Web of Science Citations: 27.

PAES, LISVANE SILVA; MANTILLA, BRIAN SUAREZ; BARISON, MARIA JULIA; WRENGER, CARSTEN; SILBER, ARIEL MARIANO. The Uniqueness of the Trypanosoma cruzi Mitochondrion: Opportunities to Target New Drugs Against Chagas' Disease. CURRENT PHARMACEUTICAL DESIGN, v. 17, n. 20, p. 2074-2099, . Web of Science Citations: 14.

BARISON, M. J.; DAMASCENO, F. S.; MANTILLA, B. S.; SILBER, A. M.. The active transport of histidine and its role in ATP production in Trypanosoma cruzi. Journal of Bioenergetics and Biomembranes, v. 48, n. 4, p. 437-449, . Web of Science Citations: 8. (13/18970-6)

BARISON, MARIA JULIA; RAPADO, LUDMILA NAKAMURA; MERINO, EMILIO F.; FURUSHO PRAL, ELIZABETH MIEKO; MANTILLA, BRIAN SUAREZ; MARCHESE, LETICIA; NOWICKI, CRISTINA; SILBER, ARIEL MARIANO; CASSERA, MARIA BELEN. Metabolomic profiling reveals a finely tuned, starvation-induced metabolic switch in Trypanosoma cruzi epimastigotes. Journal of Biological Chemistry, v. 292, n. 21, p. 8964-8977, . Web of Science Citations: 11. (13/18970-6, 16/06034-2)

GIRARD, RICHARD M. B. M.; CRISPIM, MARCELL; STOLIC, IVANA; DAMASCENO, FLAVIA SILVA; DA SILVA, MARCELO SANTOS; FURUSHO PRAL, EIZABETH MIEKO; ELIAS, MARIA CAROLINA; BAJIC, MIROSLAV; SILBER, ARIEL MARIANO. An Aromatic Diamidine That Targets Kinetoplast DNA, Impairs the Cell Cycle in Trypanosoma cruzi, and Diminishes Trypomastigote Release from Infected Mammalian Host Cells. Antimicrobial Agents and Chemotherapy, v. 60, n. 10, p. 5867-5877, . Web of Science Citations: 3. (13/07467-1, 13/18970-6)

CRISPIM, MARCELL; DAMASCENO, FLAVIA SILVA; HERNANDEZ, AGUSTINO; BARISON, MARIA JULIA; SAUTER, ISMAEL PRETTO; PAVANI, RAPHAEL SOUZA; MOURA, ALEXANDRE SANTOS; FURUSHO PRAL, ELIZABETH MIEKO; CORTEZ, MAURO; ELIAS, MARIA CAROLINA; et al. The glutamine synthetase of Trypanosoma cruzi is required for its resistance to ammonium accumulation and evasion of the parasitophorous vacuole during host-cell infection. PLoS Neglected Tropical Diseases, v. 12, n. 1, . Web of Science Citations: 4. (13/07467-1, 16/06034-2, 16/50050-2, 15/10580-0, 14/10443-0)

MANCHOLA, NUBIA CAROLINA; SILBER, ARIEL MARIANO; NOWICKI, CRISTINA. The Non-Canonical Substrates of Trypanosoma cruzi Tyrosine and Aspartate Aminotransferases: Branched-Chain Amino Acids. Journal of Eukaryotic Microbiology, v. 65, n. 1, p. 70-76, . Web of Science Citations: 2. (13/18970-6, 16/06034-2)

KRISHNA NAGAMPALLI, RAGHAVENDRA SASHI; NECIOSUP QUESNAY, JOSE EDWIN; ADAMOSKI, DOUGLAS; ISLAM, ZEYAUL; BIRCH, JAMES; SEBINELLI, HEITOR GOBBI; BRUNO MOREIRA GIRARD, RICHARD MARCEL; RODRIGUES ASCENCAO, CAROLLINE FERNANDA; FALA, ANGELA MARIA; PAULETTI, BIANCA ALVES; et al. Human mitochondrial pyruvate carrier 2 as an autonomous membrane transporter. SCIENTIFIC REPORTS, v. 8, . Web of Science Citations: 1. (14/12663-7, 14/06954-9, 14/17820-3, 17/02391-8, 15/25832-4, 14/20673-2, 15/02734-7, 16/06034-2)

MANTILLA, BRIAN S.; MARCHESE, LETICIA; CASAS-SANCHEZ, AITOR; DYER, NAOMI A.; EJEH, NICHOLAS; BIRAN, MARC; BRINGAUD, FREDERIC; LEHANE, MICHAEL J.; ACOSTA-SERRANO, ALVARO; SILBER, ARIEL M.. Proline Metabolism is Essential for Trypanosoma brucei brucei Survival in the Tsetse Vector. PLOS PATHOGENS, v. 13, n. 1, . Web of Science Citations: 20. (11/22697-8, 16/06034-2)

GIORDANA, LUCILA; MANTILLA, BRIAN SUAREZ; SANTANA, MARIANELA; SILBER, ARIEL M.; NOWICKI, CRISTINA. Cystathionine gamma- lyase, an Enzyme Related to the Reverse Transsulfuration Pathway, is Functional in Leishmania spp. Journal of Eukaryotic Microbiology, v. 61, n. 2, p. 204-213, . Web of Science Citations: 7.

DAMASCENO, FLAVIA SILVA; BARISON, MARIA JULIA; FURUSHO PRAL, ELISABETH MIEKO; PAES, LISVANE SILVA; SILBER, ARIEL MARIANO. Memantine, an Antagonist of the NMDA Glutamate Receptor, Affects Cell Proliferation, Differentiation and the Intracellular Cycle and Induces Apoptosis in Trypanosoma cruzi. PLoS Neglected Tropical Diseases, v. 8, n. 2, . Web of Science Citations: 7.

MERLI, MARCELO L.; PAGURA, LUCAS; HERNANDEZ, JOSEFINA; JULIA BARISON, MARIA; PRAL, ELIZABETH M. F.; SILBER, ARIEL M.; CRICCO, JULIA A.. The Trypanosoma cruzi Protein TcHTE Is Critical for Heme Uptake. PLoS Neglected Tropical Diseases, v. 10, n. 1, . Web of Science Citations: 3. (13/18970-6)

GALVEZ ROJAS, ROBERT L.; AHN, IL-YOUNG; MANTILLA, BRIAN SUAREZ; SANT'ANNA, CELSO; FURUSHO PRAL, ELIZABETH MIEKO; SILBER, ARIEL MARIANO. The Uptake of GABA in Trypanosoma cruzi. Journal of Eukaryotic Microbiology, v. 62, n. 5, p. 629-636, . Web of Science Citations: 5. (13/18970-6)

SANTOS SOUZA, HIGO FERNANDO; REAL, DANIEL; LEONARDI, DARIO; ROCHA, SANDRA CARLA; ALONSO, VICTORIA; SERRA, ESTEBAN; SILBER, ARIEL MARIANO; JAVIER SALOMON, CLAUDIO. Development andin vitro/in vivoevaluation of a novel benznidazole liquid dosage form using a quality-by-design approach. TROPICAL MEDICINE & INTERNATIONAL HEALTH, v. 22, n. 12, p. 1514-1522, . Web of Science Citations: 1. (13/18970-6, 16/06034-2)

MANCHOLA, NUBIA C.; RAPADO, LUDMILA N.; BARISON, MARIA J.; SILBER, ARIEL M.. Biochemical Characterization of Branched Chain Amino Acids Uptake in Trypanosoma cruzi. Journal of Eukaryotic Microbiology, v. 63, n. 3, p. 299-308, . Web of Science Citations: 10. (13/18970-6)

BOSCARDIN, SILVIA BEATRIZ; TROCCOLI TORRECILHAS, ANA CLAUDIA; MANARIN, ROMINA; REVELLI, SILVIA; GONZALEZ REY, ELENA; TONELLI, RENATA ROSITO; SILBER, ARIEL MARIANO. Chagas' disease: an update on immune mechanisms and therapeutic strategies. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, v. 14, n. 6B, p. 1373-1384, . Web of Science Citations: 24. (07/08648-9)

DE MELO GODOY, PATRICIA DIOGO; NOGUEIRA-JUNIOR, LUIS ANTONIO; PAES, LISVANE S.; CORNEJO, ALBERTO; MARTINS, RAFAEL MIYAZAWA; SILBER, ARIEL M.; SCHENKMAN, SERGIO; ELIAS, M. CAROLINA. Trypanosome Prereplication Machinery Contains a Single Functional Orc1/Cdc6 Protein, Which Is Typical of Archaea. Eukaryotic Cell, v. 8, n. 10, p. 1592-1603, . Web of Science Citations: 41.

PAES, LISVANE S.; ROJAS, ROBERT L. GALVEZ; DALIRY, ANISSA; FLOETER-WINTER, LUCILE M.; RAMIREZ, MARCEL I.; SILBER, ARIEL M.. Active Transport of Glutamate in Leishmania (Leishmania) amazonensis. Journal of Eukaryotic Microbiology, v. 55, n. 5, p. 382-387, . Web of Science Citations: 7.

MANTILLA, BRIAN S.; PAES, LISVANE S.; PRAL, ELIZABETH M. F.; MARTIL, DAIANA E.; THIEMANN, OTAVIO H.; FERNANDEZ-SILVA, PATRICIO; BASTOS, ERICK L.; SILBER, ARIEL M.. Role of Delta(1)-Pyrroline-5-Carboxylate Dehydrogenase Supports Mitochondrial Metabolism and Host-Cell Invasion of Trypanosoma cruzi. Journal of Biological Chemistry, v. 290, n. 12, p. 7767-7790, . Web of Science Citations: 21. (13/18970-6)

PARIONA-LLANOS, RICARDO; PAVANI, RAPHAEL SOUZA; REIS, MARCELO; NOEL, VINCENT; SILBER, ARIEL MARIANO; ARMELIN, HUGO AGUIRRE; CANO, MARIA ISABEL NOGUEIRA; ELIAS, MARIA CAROLINA. Glyceraldehyde 3-Phosphate Dehydrogenase-Telomere Association Correlates with Redox Status in Trypanosoma cruzi. PLoS One, v. 10, n. 3, . Web of Science Citations: 11. (13/07467-1)

NDJONKA, DIEUDONNE; RAPADO, LUDMILA NAKAMURA; SILBER, ARIEL M.; LIEBAU, EVA; WRENGER, CARSTEN. Natural Products as a Source for Treating Neglected Parasitic Diseases. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v. 14, n. 2, p. 3395-3439, . Web of Science Citations: 71. (09/54325-2)

WRENGER, CARSTEN; MUELLER, INGRID B.; SILBER, ARIEL M.; JORDANOVA, ROSITSA; LAMZIN, VICTOR S.; GROVES, MATTHEW R.. Aspartate Aminotransferase - Bridging Carbohydrate and Energy Metabolism in Plasmodium Falciparum. CURRENT DRUG METABOLISM, v. 13, n. 3, p. 332-336, . Web of Science Citations: 8.

BUCHENSKY, CELESTE; ALMIRON, PAULA; MANTILLA, BRIAN SUAREZ; SILBER, ARIEL M.; CRICCO, JULIA A.. The Trypanosoma cruzi proteins TcCox10 and TcCox15 catalyze the formation of heme A in the yeast Saccharomyces cerevisiae. FEMS Microbiology Letters, v. 312, n. 2, p. 133-141, . Web of Science Citations: 11.

MARCIANO, DANIELA; SANTANA, MARIANELA; MANTILLA, BRIAN SUAREZ; SILBER, ARIEL MARIANO; MARINO-BUSLJE, CRISTINA; NOWICKI, CRISTINA. Biochemical characterization of serine acetyltransferase and cysteine desulfhydrase from Leishmania major. Molecular and Biochemical Parasitology, v. 173, n. 2, p. 170-174, . Web of Science Citations: 6.

STOLIC, IVANA; MISKOVIC, KATARINA; MAGDALENO, ANAHI; SILBER, ARIEL MARIANO; PIANTANIDA, IVO; BAJIC, MIROSLAV; GLAVAS-OBROVAC, LJUBICA. Effect of 3,4-ethylenedioxy-extension of thiophene core on the DNA/RNA binding properties and biological activity of bisbenzimidazole amidines. Bioorganic & Medicinal Chemistry, v. 17, n. 6, p. 2544-2554, . Web of Science Citations: 24.

MAGDALENO, ANAHI; AHN, IL-YOUNG; PAES, LISVANE SILVA; SILBER, ARIEL M.. Actions of a Proline Analogue, L-Thiazolidine-4-Carboxylic Acid (T4C), on Trypanosoma cruzi. PLoS One, v. 4, n. 2, . Web of Science Citations: 34.

ALEJANDRO PEREIRA, CLAUDIO; SILBER, ARIEL MARIANO. On the Evolution of Hexose Transporters in Kinetoplastid Potozoans. PLoS One, v. 7, n. 5, . Web of Science Citations: 2.

SILBER, ARIEL MARIANO; ALEJANDRO PEREIRA, CLAUDIO. Assignment of Putative Functions to Membrane ``Hypothetical Proteins{''} from the Trypanosoma cruzi Genome. Journal of Membrane Biology, v. 245, n. 3, p. 125-129, . Web of Science Citations: 4.

GIRARD, RICHARD M. B. M.; CRISPIM, MARCELL; ALENCAR, MAYKE BEZERRA; SILBER, ARIEL MARIANO. Uptake of L-Alanine and Its Distinct Roles in the Bioenergetics of Trypanosoma cruzi. MSPHERE, v. 3, n. 4, . Web of Science Citations: 2. (16/06034-2, 17/16553-0)

MARCHESE, LETICIA; NASCIMENTO, JANAINA DE FREITAS; DAMASCENO, FLAVIA SILVA; BRINGAUD, FREDERIC; MICHELS, PAUL A. M.; SILBER, ARIEL MARIANO. The Uptake and Metabolism of Amino Acids, and Their Unique Role in the Biology of Pathogenic Trypanosomatids. PATHOGENS, v. 7, n. 2, . Web of Science Citations: 2. (16/06034-2, 17/16553-0)

AVILA, CARLA CRISTI; MULE, SIMON NGAO; ROSA-FERNANDES, LIVIA; VINER, ROSA; BARISON, MARIA JULIA; COSTA-MARTINS, ANDRE GUILLHERME; DE OLIVEIRA, GILBERTO SANTOS; GERALDES TEIXEIRA, MARTA MARIA; FARIAS MARINHO, CLAUDIO ROMERO; SILBER, ARIEL MARIANO; et al. Proteome-Wide Analysis of Trypanosoma cruzi Exponential and Stationary Growth Phases Reveals a Subcellular Compartment-Specific Regulation. GENES, v. 9, n. 8, . Web of Science Citations: 0. (16/06034-2, 14/06863-3)

DAMASCENO, FLAVIA S.; BARISON, MARIA JULIA; CRISPIM, MARCELL; SOUZA, RODOLPHO O. O.; MARCHESE, LETICIA; SILBER, ARIEL M.. L-Glutamine uptake is developmentally regulated and is involved in metacyclogenesis in Trypanosoma cruzi. Molecular and Biochemical Parasitology, v. 224, p. 17-25, . Web of Science Citations: 0. (16/06034-2, 17/16553-0)

SILBER, ARIEL M.; GALVEZ ROJAS, ROBERT L.; URIAS, URSULA; COLLI, WALTER; ALVES, MARIA JÚLIA MANSO. Biochemical characterization of the glutamate transport in Trypanosoma cruzi. International Journal for Parasitology, v. 36, n. 2, p. 157-163, . (04/03303-5)

GALVEZ ROJAS‚ R.L.; FROSSARD‚ M.L.; MACHADO MOTTA‚ M.C.; SILBER‚ A.M.. l-Proline uptake in Crithidia deanei is influenced by its endosymbiont bacterium. FEMS Microbiology Letters, v. 283, n. 1, p. 15-22, .

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