CV Lattes
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Universidade de São Paulo (USP). Faculdade de Ciências Farmacêuticas de Ribeirão Preto (FCFRP) (Institutional affiliation from the last research proposal) Birthplace: Brazil
bachelor's at Medicina Veterinaria from Universidade de São Paulo (1993), master's at Parasitology from Universidade de São Paulo (1997) and doctorate at Parasitology from Universidade de São Paulo (2001). Has experience in Veterinary Medicine, focusing on Parasitic Illnesses of Animals, acting on the following subjects: secreted proteins, babesia bovis, host cell invasion, medicamento and proteomics. (Source: Lattes Curriculum)
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Neospora caninum (Nc) is an obligatory intracellular parasite that belongs to the Phylum Apicomplexa. It is the etiological agent of neosporosis, a treatment-challenging disease that causes abortion in cattle. The economic losses caused to cattle industry by neosporosis, associated to the absence of treatment to control this parasitic disease, spotlights Nc as an important investigation t…
Neospora caninum is an Apicomplexan protozoan, obligatory intracellular parasite that has the dog as definitive host and especially cattle as intermediate hosts. Galectin-1, a beta-galactoside-binding protein, shows an immunomodulation effect in different models of inflammatory and autoimmune diseases. However the galectin-1 role during the parasite infection has not been completely eluci…
The apicomplexan protozoan Neospora caninum (Nc), the etiological agent of Neosporosis, is associated with neurological symptoms in dogs and abortion in cattle. This disease is worldwide spread and has no efficient treatment. The survival and replication of the parasite depends on an enzymatic antioxidant system defense for evading the oxidative stress inside the host cell. Among these en…
Neospora caninum is an Apicomplexan protozoan that infects, among a whole range of intermediate hosts, bovine where it is emerging as a relevant cause of reproductive problems and abortion in dairy and beef cattle. As obligatory intracellular organisms, Apicomplexan parasites use their own active locomotion system to move and invade host cells. This mechanism is driven by the actin/myosin…
Fatty acylated proteins are critical players in signalling in both normal cells and disease states, including infectious diseases. S-acylation (S-palmitoylation) is an abundant and relevant Post Translation Modification (PTM) in apicomplexan parasites. This PTM is added by Protein S-AcylTransferases (DHHC-PATs), transmembrane proteins with a catalytic amino acid motif DHHC (Asp-His-His-Cy…
Neospora caninum, an apicomplexan parasite, is one of the main causes of infectious abortion in cows, leading to significant economic losses to cattle breeders. As obligatory intracellular organisms, apicomplexans need to migrate into the cells to survive. The filamentous form of actin (f-actin) has a central role in the generation of the invasion and gliding motility at the motor complex…
| 5 / 2 | Completed research grants |
| 9 / 3 | Completed scholarships in Brazil |
| 2 / 2 | Completed scholarships abroad |
| 16 / 7 | All research grants and scholarships |
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