Mariane Valéria Roldão

Universidade Estadual de Campinas (UNICAMP). Instituto de Química (IQ) (Institutional affiliation from the last research proposal)
Birthplace: Brazil

Abstract
This Master's degree research project has as its main target the proposal of a new synthetic approach for the preparation of a class of anti-inflammatory substances, which were previously synthesized in our laboratory. Based on Morita-Baylis-Hillman adducts, we developed a synthetic strategy that allowed the synthesis of a small series of compounds presenting a very promising anti-inflamm…
New synthetic approach for the preparation of non-steroidal anti-inflammatory drugs, selective COX-2 inhibitors: study of mechanisms of anti-inflammatory action, BP.MS
Abstract
Parabens are neutral esters derived from p-hydroxybenzoic acid and at low concentrations (0.016 to 0.4%) they inhibit the development of microorganisms in cosmetic products. In the skin, the esterase enzyme hydrolyses the parabens present in cosmetics of topical use. However, incomplete hydrolysis may occur in the presence of large amounts of parabens, which may accumulate in the human bo…
Development of molecularly imprinted extraction phase for analysis of parabens in plasma samples by liquid chromatography coupled to mass spectrometry sequence, BP.IC

CV Lattes

2 / 2	Completed scholarships in Brazil

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