CV Lattes
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Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. Escola Paulista de Medicina (EPM) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Doctor of Veterinary Medicine graduated at University of São Paulo (USP, 1995), MSc in Veterinary Medicine (USP, 1999) and PhD in Compared and Experimental Pathology (USP, 2004). Research Fellow at the Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School from January 2005 to December 2007. Started in 2008 as Assistant Professor at the Department of Microbiology, Immunology and Parasitology, Federal University of São Paulo, UNIFESP. (Source: Lattes Curriculum)
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The nervous system can interact with the immune system via the sympathetic nervous system (SNS). It has been already described that lymphoid organs are richly innervated by sympathetic fibers, which exert their actions by releasing mainly catecholamines. The anatomy of the sympathetic innervation in lymphoid organs such as the spleen and lymph nodes suggests that many immune processes, in…
The nervous system can interact with the immune system via the sympathetic nervous system (SNS). It has been already described that lymphoid organs are richly innervated by sympathetic fibers, which exert their actions by releasing mainly noradrenaline. The anatomy of the sympathetic innervation in lymphoid organs such as the spleen and lymph nodes suggests that many immune processes, inc…
The nervous system can interact with the immune system via the sympathetic nervous system (SNS). It has been already described that lymphoid organs are richly innervated by sympathetic fibers, which exert their actions by releasing mainly catecholamines. The anatomy of the sympathetic innervation in lymphoid organs such as the spleen and lymph nodes suggests that many immune processes, in…
(Only some records are available in English at this moment)
Included in a large group of autoimmune diseases, Multiple Sclerosis (MS) affected about 2.8 million people globally by the year 2020, according to data from the National Multiple Sclerosis Society (2020). MS is a potentially disabling pathology because it greatly affects the Central Nervous System (CNS), and thus promotes the observed clinical symptoms. This is because the immune system …
Multiple Sclerosis (MS) is an autoimmune disease characterized by the progressive loss of movements; one of its hallmarks is the demyelization of myelin sheaths that protects neurons in the Central Nervous System (CNS). The physiopathology of MS is not yet well elucidated and its treatment does not lead to cure, instead it only ameliorates the symptoms, and can also cause side effects suc…
The interplay between the Nervous System (NS) and the immune system (IS) has been studied during the last thirty years. In particular, the regulation of the immune system by the Sympathetic Nervous System (SNS) has received a lot of attention. Immune cells express both alfa and beta adrenergic receptors, which enables them to respond to SNS stimulus. The objective of this project is to st…
It is has been already established in the literature that the nervous system interacts with the immune system and these interactions could modulate immunological responses upon different stimulus. This project has as objective to investigate the consequences of this interaction in the macrophage polarization towards M1 or M2. The known Macrophages M1 are cells with a pro-inflammatory prof…
(Only some records are available in English at this moment)
Macrophages are very heterogeneous immune cells that are responsible for the maintenance of tissue homeostasis. Upon tissue injury or infection, macrophages are promptly activated and start to orchestrate the innate immune response, mediated in part by the production of chemokines and cytokines to attract and activate other immune cells. Metabolic reprogramming is an essential process for…
The interplay between the nervous system and the immune system has been studied for the past thirty years, but our knowledge of the regulation of the immune system by the sympathetic nervous system (SNS) remains incomplete. Cells of the innate immune system, including macrophages, express both ± and ² adrenergic receptors, which enables them to respond to adrenergic signals from the sympa…
| 5 / 4 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 8 / 6 | Completed scholarships in Brazil |
| 2 / 2 | Completed scholarships abroad |
| 16 / 13 | All research grants and scholarships |
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