CV Lattes
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Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Undergraduate in Biological Sciences - Medical Modality, Universidade Estadual Paulista Júlio de Mesquita Filho (1997), with Master Degree (2000) and PhD (2004) in Basic and Applied Immunology, University of São Paulo, and Post-Doctoral Fellow at the Laboratory of Malaria and Vector Research, National Institutes of Allergy and Infectious Diseases-NIH (2005-2009). Full Professor (MS-6) at the Departament of Immunology, Institute of Biomedical Sciences, University of Sao Paulo (ICB/USP) and head of the Laboratory of Experimental Immunology. Visiting Professor at the Department of Medicine, Vanderbilt University Medical Center (2019-2020). Former Vice-Coordinator (2010-2015) and Coordinator (2015-2017) of the Institutional Animal Care and Use Committee, General Comptroller at ICB/USP (2018-2019 and 2020-2025), Vice-Coordinator (2013-2017 and 2022-2023) and Coordinator (2023-current) of the Immunology Graduate Program at ICB/USP. Member of the Brazilian Society of Immunology. Fields of interest: inflammation, acquired immunity, medical entomology and immunomodulatory activities from saliva of hematophagous arthropods vectors of diseases. (Source: Lattes Curriculum)
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Among the tick species present in Brazil, those of the Amblyomma genus present the greatest abundance and distribution in the country. Amblyomma sculptum is endemic in the Southeast region and has capybaras, tapirs and horses as hosts, in addition to the potential to parasitize humans. This species is responsible for the transmission of the bacterium Rickettsia rickettsii, which causes Br…
The saliva of female Aedes aegypti is constituted by a mixture of molecules that participate of the combat against the host's hemostasis and immune system during blood feeding. Among the activities found in the saliva of this vector, there is a rapid, potent, and selective cytotoxicity to lymphocytes, recently described by our group and mediated by a molecule only present in saliva of the…
(Only some records are available in English at this moment)
Aedes aegypti is an arthropod from the Culicidae family, distributedworldwide. This mosquito is the vector of arboviruses that cause yellow fever,Zika, chikungunya and dengue, which together are responsible for the deaths ofthousands of individuals every year. The Ae. aegypti uses glucose obtainedfrom plant nectar as the main energy source for its metabolism. However,females of the specie…
Aedes spp. mosquitoes, especially Aedes aegypti, are endemic in several parts of the world, mainly in tropical and subtropical regions. Its presence and dissemination generate an alert, as it is a vector of several arboviruses such as dengue fever, yellow fever, Zika, and chikungunya. The transmission of these diseases occurs during the blood feeding of female mosquitoes and the success o…
Amblyomma spp. include the ticks with the largest abundance and distribution in Brazil. More specifically, Amblyomma sculptum, a species endemic to the southeast region, is an important parasite of several vertebrates, including humans. These ticks have high clinical relevance due to the transmission of pathogens such as Rickettsia rickettsii, a bacterium that causes Brazilian spotted fev…
The saliva of female Aedes aegypti is constituted by a mixture of molecules that participate in the combat against the host hemostatic and immune system during blood feeding, facilitating the ingestion of blood and inhibiting factors that can prevent proper feeding. Pathogens can take advantage of this saliva peculiarity to settle in the host and cause disease. Among the activities presen…
(Only some records are available in English at this moment)
Amblyomma spp. include the ticks with the largest abundance and distribution in Brazil. More specifically, Amblyomma sculptum, a species endemic to the southeast region, is an important parasite of several vertebrates including humans. These ticks are of clinical relevance due to the transmission of pathogens such as Rickettsia rickettsii, the causative agent of Brazilian spotted fever, a…
Aedes aegypti is a cosmopolitan mosquito species that transmits arboviruses that cause emerging and re-emerging diseases such as yellow fever, dengue, chikungunya and Zika. When attempting to feed on a vertebrate host, the Ae. aegypti mouthparts are inserted into the skin and saliva is deposited in this microenvironment, assisting in the location of blood vessels and counteracting molecul…
T lymphocytes play a fundamental role in the adaptive immune response against pathogens by destroying infected cells, secreting cytokines that help the activation of other cells, and regulating the activity of these cells. On the other hand, they are also involved in the pathology of certain diseases such as autoimmunity, hypersensitivity reactions, transplant rejection and lymphomas. Imm…
| 11 / 6 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 20 / 14 | Completed scholarships in Brazil |
| 3 / 3 | Completed scholarships abroad |
| 35 / 24 | All research grants and scholarships |
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