CV Lattes
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Universidade de São Paulo (USP). Faculdade de Medicina de Ribeirão Preto (FMRP) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Graduated in Medicine from the School of Medicine of the University of São Paulo (1983), Medical Residency in Infectious Diseases at the Hospital das Clínicas of the School of Medicine of the University of São Paulo, Master in Epidemiology and Public Health (Virology major) from Yale University (1989 ) and PhD in Molecular Virology - Yale University (1994). He is currently an associate professor (Level III) at the Ribeirão Preto School of Medicine, University of São Paulo. He has experience in the field of Medicine, with an emphasis on Infectious and Parasitic Diseases, acting mainly on the following themes: epidemiology, clinical manifestations and diagnosis of dengue and other arboviruses; use of molecular virology techniques with special attention to the production of diagnostic reagents and vaccine candidates against dengue and other arboviruses; assessment of the immune response induced by viral infections. (Source: Lattes Curriculum)
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This thematic research project is proposed based on a central backbone of research on viruses of great importance for human health. The proposal comes from five collaborative research groups, led by established professors, and consists of subprojects distributed in four major areas of work: 1) Virus-cell interaction; 2) Pathogenesis of viral infections; 3) Diagnosis and prospection of hum…
Yellow Fever is a disease caused by the Yellow Fever Virus (YFV), an arbovirus (arthropod-borne virus) that belongs to family Flaviviridae, genus Flavivirus, and considered the prototype of this family. Yellow Fever transmission is characterized by an urban and a sylvatic cycle of transmission, depending on the vector responsible for the transmission. Similar to other flaviviruses, YFV ge…
The dengue (DENV) and yellow fever (YFV) viruses are the main arboviruses (arthropod-borne viruses) circulating in Brazil. They are transmitted by mosquitoes of the genus Aedes and cause the diseases called dengue and yellow fever, respectively. Dengue is currently the human disease transmitted by an arbovirus of greatest significance to public health worldwide. These viruses are prevalen…
Dengue fever results from infection by any of the dengue virus (DENV), and it is considered the main arbovirus infection worldwide, and an extremely important one for our country. Dengue has a wide variety of clinical symptoms, ranging from asymptomatic infections to severe forms called dengue hemorrhagic fever / dengue shock syndrome (DHF / DSS). The pathogenesis of dengue infections, an…
(Only some records are available in English at this moment)
We have demonstrated in a previous study that the SPP1 gene was positively modulated in vitro after infection with MAYV, which is a virus different from other arthritogenic viruses from the same family, as it induces a more attenuated inflammatory response. This may result from differential modulation of SPP1. The SPP1 gene encodes osteopontin, a protein that has several functions, such …
West Nile Virus (WNV) is an emerging arbovirus, which was first detected in Northeastern Brazil in 2014. Four years later it was detected in the Southeastern region, affecting three horses. In 2019, another horse was reported in the state of Minas Gerais and the confirmation of the first human death caused by WNV in Brazil, although it was a 2017 case. The enzootic cycle is maintained bet…
The recent outbreak caused by chikungunya virus (Alphavirus, Togaviridae) worldwide has shown that, despite being first isolated in the 1950s, this infection still has several points to be elucidated, especially regarding the correct diagnosis of the disease caused by this virus, but also treatment and prevention of infection. The virus, which in spite of short viremia, produces symptoms …
Zika Fever is a disease that affects many people in tropical and subtropical countries. The etiologic agent is Zika Virus (ZIKV), a single-stranded RNA flavivirus, transmitted mostly by Aedes mosquitoes, but sexual, congenital and blood transfusion transmission has also been reported. Due to the possible association of ZIKV to microcephaly and Guillain-Barré Syndrome, it is necessary to d…
(Only some records are available in English at this moment)
The recent outbreak caused by chikungunya virus (Alphavirus, Togaviridae) worldwide has shown that, despite being first isolated in the 1950s, this infection still has several points to be elucidated. This especially includes the correct diagnosis of the disease caused by the virus, but also treatment and prevention of infection. The virus, which in spite of short-lived viremia, produces …
| 1 / 1 | Ongoing grants |
| 18 / 7 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 26 / 7 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 47 / 17 | All research grants and scholarships |
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