CV Lattes
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Universidade de São Paulo (USP). Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto (FFCLRP) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Holds a degree in Pharmacy-Biochemistry from the Hermínio Ometto College, a PhD in Toxicology from the Faculty of Pharmaceutical Sciences of Ribeirão Preto (FCFRP-USP) and a post-doctorate from the University of São Paulo. He is currently an Associate Professor 1 in the Chemistry Department of the Faculty of Philosophy, Sciences and Letters of Ribeirão Preto (FFCLRP-USP). He works in the area of #8203;#8203;Analytical Chemistry, with an emphasis on the stereoselective separation of pesticides, drugs and metabolites by high-performance liquid chromatography (HPLC) and capillary electrophoresis, validation of analytical methods, development of miniaturized sample preparation techniques and in vitro metabolism studies. The group's research line is focused on the development of chromatographic and electrophoretic methods applied to the investigation of biotransformations and metabolic interactions in vitro.More information about the research group is available at: http://armdeoliveira.wixsite.com/labmets (Source: Lattes Curriculum)
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In this new proposal, we aim to continue the project started previously (FAPESP 2018-07534-4) whose validity ended on 03/31/2021. The main objective of this project is the in vitro determination of enantioselectivity in the metabolism and enzymatic inhibition of chiral pesticides on the main cytochrome P450 (CYP450) enzymes involved in drug metabolism. These studies will be conducted with…
Quantification of analytes present in biological matrices requires the development of methods that are accurate and reproducible under various analytical conditions. Chromatographic and electrophoretic techniques (capillary electrophoresis) are techniques widely used for these purposes. These techniques have the main advantage of simplicity, rapid analysis and wide versatility. Our resear…
The quantification of analytes present in biological matrices requires the development of accurate and reproducible analytical methods under several conditions of analysis. Chromatographic and electrophoretic techniques (capillary electrophoresis) are techniques widely used for these purposes. These techniques have several advantages such as: simplicity, speed of the analysis and versatil…
(Only some records are available in English at this moment)
Glyphosate is the most widely used pesticide in Brazil and worldwide and is used in many crops, such as rice, coffee, sugarcane, beans, corn, soybeans and wheat. Due to its massive use in agriculture and frequent use in the composition of household cleaning products, several studies have warned about the contamination of water bodies, atmospheric air and food. As a result, there is great …
UV filters, present in sunscreen lotions and creams, are widely used in the population's daily lives, as they can absorb the ultraviolet radiation emitted by the sun and prevent human skin from possible damage caused by excessive and prolonged exposure. Among the main substances present in sunscreens, with the function of UV filter, the project focuses on the study of octocrylene, a UV fi…
Acephate (ACE) is an organophosphate insecticide used mainly on vegetable and fruit crops, such as potatoes, citrus, melon and tomatoes. Studies indicate that this pesticide is one of the most consumed and the presence of its residues in the environment and in food is undeniable, as is the risk associated with it in terms of public health. Additionally, given the significant use of medica…
Methamidophos is a chiral pesticide whose enantioselective effects have already been observed under different environmental conditions and in vitro assays. In addition, it has been widely used for pest control in peanut, tomato, potato, bean, cotton, soybean and wheat plantations. Currently, as a pesticide, it has been banned in several countries due to its high degree of toxicity. Even w…
The intense use of pesticides in agricultural areas around the world exposes serious risks to the environment and human beings. The identification of water and food contaminated with penconazole shows that exposure of non-target species occurs and is of great concern. In vitro metabolism models can be used to evaluate pesticide metabolism. This technique has several advantages such as the…
(Only some records are available in English at this moment)
Pesticide exposure represents a significant health concern with significant impacts reported for both acute and chronic exposure. Pesticide-drug interactions are believed to play a role in the toxicity of pesticides due to the inhibition of CYP450 forms responsible for drug metabolism by pesticides. These interactions can lead to adverse effects or even lack of drug activity due to the in…
Greening is a citrus plant disease caused by gram-negative bacteria and transmitted by insect vectors. Citrus greening disease has a severe impact in the citrus worldwide production. The economic loss caused by this disease, both in Brazil and the United States of America, is extremely significative with great revenue losses. There are no known curative methods to combat the citrus greeni…
| 6 / 6 | Completed research grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 18 / 18 | Completed scholarships in Brazil |
| 2 / 2 | Completed scholarships abroad |
| 28 / 28 | All research grants and scholarships |
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