Isabel Maria Vicente Guedes de Carvalho Mello

CV Lattes ResearcherID ORCID Google Scholar Citations

Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. Escola Paulista de Medicina (EPM) (Institutional affiliation from the last research proposal)
Birthplace: Moçambique

graduate at Bacharel e Licenciatura Em Ciências Biológicas from Universidade Gama Filho (1986), master's at Microbiologia e Imunologia from Universidade Federal do Rio de Janeiro (1992) and ph.d. at Pathological Anatomy and Clinical Pathology from Universidade de São Paulo (2006). Has experience in Microbiology, focusing on Virology, acting on the following subjects: hepatitis c virus, genotypes, hepatitis b virus, peginterferon and hbv. (Source: Lattes Curriculum)

News published in Agência FAPESP Newsletter about the researcher

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Research grants

Completed (most recent)

Abstract
Aedes aegypti and Aedes albopictus are important vectors in the transmission of several arboviruses. Among medical important arthropod bourne viruses, the most important are the the Flavivirus genus (Flaviviridae family) such as dengue (DENV) virus, Zika virus (ZIKV), Yellow fever virus (YF) and encephalitis virus Saint Louis (SLEV) which are a very important topic in public health today.…
Natural vertical transmission of medical interest Flavivirus in Aedes aegypti and Aedes albopictus, AP.R
HEPATITIS C VIRUS PRIMARY MUTATIONS RELATED TO RESISTANCE TO PROTEASE AND POLYMERASE INHIBITORS IN CHRONIC PATIENTS FROM SÃO PAULO CITY,BRAZIL, AP.R
Pre-treatment genetic variability of ns5a region on patients infected with hcv genotype, AR.EXT

Scholarships in Brazil

Completed (most recent)

Abstract
The therapy for patients with hepatitis C, for more than a decade, was based in the use of conventional interferon (IFN) or pegylated interferon (IFN-PEG) combined with ribavirin (RBV), administered for 24 or 48 weeks depending on the infecting genotype. Due to this, it is of extreme importance to recognize the mechanism behind the therapy, because even today its real functioning is unkno…
Antiviral therapy: impact on HCV genetic diversity in Chronic Kidney Disease patients, BP.IC
Abstract
The difficulties related to diagnosis and treatment against hepatitis C virus (HCV) infection has stimulated researches in drugs development area. New treatments have as main feature the virus direct inhibition by preventing the function of proteins scents in its replication. The new treatments unique mechanism of function makes the knowledge of molecular characteristics extreme important…
Molecular Characterization of Hepatite C Virus from renal chronic disease patients under hemodialysis, BP.MS
In silico analyses of primary mutations in sequences of cronical infected patients by HCV obtained from public databanks for resistance to the protease (NS3) and polymerase (NS5B) inhibitors., BP.IC

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Total / Available in English

4 / 3	Completed research grants
4 / 4	Completed scholarships in Brazil
8 / 7	All research grants and scholarships

Associated processes

Most frequent collaborators in research granted by FAPESP

Keywords used by the researcher

Biochemistry Biological Sciences Biology Genetics Microbiology

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Abstract

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Abstract