CV Lattes
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Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduate at Medicina from Faculdade de Medicina da Usp Sp (1998) and ph.d. at Doutorado Direto Concentração Em Cardiologia from Instituto do Coração (2007). Has experience in Medicine, focusing on Cardiology, acting on the following subjects: nad(p)h oxidase, oxidative stress, cardiologia clínica, cardiologia and atherosclerosis. (Source: Lattes Curriculum)
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Increased human longevity potentiates Vascular Calcification (VC) complications. Epidemiological studies show that VC increases the risk of lower limb amputations (AMI) in patients with Peripheral Arterial Disease (PAD). Moreover, VC is commonly associated with factors such as aging and the presence of Diabetes Mellitus (DM). Researchers have been using Hutchinson-Gilford syndrome (HGPS) …
Obstructive atherosclerotic lesions of vessels distal to aortic bifurcation (iliac artery), decreasing oxygen delivery to tissues is the hallmark of obstructive peripheral arterial disease (PAD). The most important complication of PAD is extremity amputation, in which peripheral arterial insufficiency (ischemia) participates of its pathophysiology in 80% of cases. Amputations due to PAD o…
Vascular calcification is an important clinical disease which increases cardiovascular morbidity and mortality, occurring frequently in both diabetes and in chronic renal failure. Previously considered a passive and chronic degenerative condition of ageing, recently it is understood as an active and complex process, with definite pathophysiology that recapitulates osteogenesis. Vascular c…
(Only some records are available in English at this moment)
Due to the increasing of human longevity, complications from Vascular Calcification (VC) became more evident. Epidemiological studies show that VC increases the risk of lower limb amputations (AMI) in patients with Peripheral Arterial Disease (PAD). Moreover, VC is commonly associated with factors such as aging and the presence of Diabetes Mellitus (DM). Researchers have been using Hutchi…
A estenose aórtica degenerativa é a principal patologia valvar adquirida no mundo ocidental e afeta mais de 3% da população com mais de 75 anos de idade, sendo, portanto, causa preponderante de morbimortalidade e de indicação de troca valvar cirúrgica. Muito se acreditou na teoria de "uso e desgaste" da valva, porém estudos da última década têm demonstrado que este tecido, na realidade, s…
A calcificação vascular é um processo fisiopatológico relevante, correlaciona-se com a aterosclerose coronária e é um marcador prognóstico de morbimortalidade e de eventos cardiovasculares. A calcificação vascular/valvar é um processo patológico presente em muitas doenças cardiovasculares, incluindo aterotrombose, hipertensão arterial sistêmica e envelhecimento. Além disso, a estenose val…