Ana de Lourdes Candolo Martinelli

• Abstract

  Hepatoceluar carcinoma (HCC) is a primary malignant tumor of the liver and represents a great public health problem worldwide. HCC is the fifth most common malignancy among men and the third leading cause of cancer death worldwide, with approximately 90% of cases associated with chronic liver disease or cirrhosis. Despite recent advances in diagnosis and treatment of HCC, early detection …

  Mechanisms of oncogenesis in chronic liver disease and hepatocellular carcinoma, AP.R
• 62nd Annual Meeting of the American Association for the Study of liver Diseases, The liver meeting 2011, AR.EXT

• Abstract

  Chronic infection with the hepatitis B virus (HBV) is common in Brazil. This disease admits serious forms of chronic hepatitis, and can lead to cirrhosis and hepatocellular carcinoma (HCC). Several factors influence the evolution of HBV infection, among them the patient's age and gender and the viral load of HBV. More recently, researches have been made about the influence of HBV genotype…

  Study of the role of hepatitis B virus (HBV) genotypes on clinical outcome, severity of liver disease and response to treatment in chronic HBV infection, AP.R

(Only some records are available in English at this moment)

• Abstract

  Hereditary hemochromatosis is the most common genetic disease among individuals with European ancestry. Two mutations, C282Y and H63D in the HFE gene are associated with HH. Approximately 85-90% of patients of European descent with HH are homozygous for C282Y. In Brazil, this percentage is unknown because of the great miscegenation. The objectives of this study are to identify individuals…

  Hereditary hemochromatosis in a University Hospital, Faculty of Medicine of Ribeirão Preto (2000-2012), BP.IC
• The role of G/T polymorphism of microsomal triglyceride transfer protein gene(MTP) and T/C of manganese superoxide dismutase gene (MnSOD) in Non Alcoholic Steatohepatitis, BP.IC