Antonio Sesso

• Abstract

  There is no consensus on whether in apoptotic HeLa cells generated by staurosporine treatment, the release to the cytoplasm of apoptogenic proteins like cytochrome c that reside in the mitochondrial intermembrane space (MIS) precedes or not the loss of the selective permeability of the inner mitochondrial membrane (IMM). Observations done by us in 02/2013 showed that in staurosporine ind…

  Structural and cytochemical changes that precede, escort and succeed the irreverssible permeabilization of the inner mitochondrial membrane in apoptotic HeLa, COS-7 and PC-12 cells. a microscopic and cytometric study, AP.R

• Abstract

  ABSTRACTOuter mitochondrial membrane (OMM) rupture was first noted inisolated mitochondria in which the inner mitochondrial membrane (IMM)had lost its selective permeability. This phenomenon referred to as mitochondrialpermeability transition (MPT) refers to a permeabilized innermembrane that originates a large swelling in the mitochondrial matrix,which distends the outer membrane until i…

  Mitochondrial Swelling and Incipient Outer Membrane Rupture in Preapoptotic and Apoptotic Cells, PUB.ART
• Mounting evidences of polarized rupture of the outer mitochondrial membrane in apoptotic cells., AR.EXT

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