graduation at Bacharelado em Química from Fundação Universidade Regional de Blumenau (1998), master's at Chemistry from Universidade Federal de Santa Catarina (2001) and doctorate at Chemistry from Universidade Estadual de Campinas (2006). (Source: Lattes Curriculum)
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The marine alkaloids halichlorine, pinnaic acid and tauropinnaic acid, isolated by Uemura and co-workers in 1996, show the common 1-aza-[4.5.0]-spirobicyclic core. The biological activity of halichlorine is related to inhibit vascular cell adhesion molecule-1 (VCAM-1) at IC50 7 mg/mL. The pinnaic acid and tauropinnaic acid are phospholipase A2 (PLA2) inhibitors. Despite the structural sim…
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CV Lattes
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