Abstract
The PANDER/FAM3B (pancreatic-derived factor) was recently identified as a novel cytokine expressed capable to induce apoptosis in insulin secreting beta-cells. However, PANDER gene is also expressed in prostate and breast tumors. Our goal is to evaluate the pro-apoptotic properties of PANDER in prostate carcinoma (DU145) and breast adenocarcinoma (MDA-MB-231) stably over-expressing PANDER…