CV Lattes
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Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. Escola Paulista de Medicina (EPM) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Graduate at Medicina from Faculdade de Medicina da Universidade Federal da Bahia (1989), Residence in Neurology from Universidade de São Paulo (1994), Ph.D. at Pathological Anatomy and Clinical Pathology from Universidade de São Paulo (1999). Experience with neuromuscular disorders, skeletal muscle pathology, malignant hyperthermia, central core disease, motor neuron disease (amyotrophic lateral sclerosis and post-polio syndrome). (Source: Lattes Curriculum)
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Malignant hyperthermia (MH) is a pharmacogenetic skeletal muscle disease expressed as a hypermetabolic response to volatile anesthetics and/or the depolarizing muscle relaxant succinylcholine and, rarely, to intense physical exercise and ambient heat. Genes linked to the excitation-muscle contraction process are involved, especially the ryanodine receptor 1 gene RYR1. In genetically susce…
The treatment of dyslipidemia received great impetus after the development of drugs that, alongside dietary measures, contribute to the reduction of serum lipids. Among these drugs are the statins, currently considered the most useful agents for the treatment of hypercholesterolemia. The statin therapy may be severely limited by side effects involving many tissues, particularly skeletal m…
The statins are currently considered the most useful agents for the treatment of hypercholesterolemia. In recent years, there have been reports of significant side effects in skeletal muscle, with myalgia, increases in serum creatine phosphokinase (CPK) and even rhabdomyolysis after using high doses of these medications. The early recognition of the myopathy induced by statins and its dis…
| 1 / 1 | Ongoing grants |
| 1 / 1 | Completed research grants |
| 3 / 1 | Completed scholarships in Brazil |
| 5 / 3 | All research grants and scholarships |
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