Roy Edward Larson

• Abstract

  Project summary. We have purified and partially characterized an RNA-binding protein of 65 kDa (p65) from optic lobes of squid (Doryteuthis pleii, South Atlantic species and Doryteuthis pealii, North Atlantic species) (Lico et al. 2010; 2015). It has been identified as a member of the heterogenous nuclear ribonucleoprotein family, subgroup A/B (hnRNPA/B). Cloning, sequencing and data mini…

  Molecular and cellular characterization of neuronal hnRNPA/B proteins, AP.R

• Abstract

  The giant synapse and axons of squid (Loligo) represent an important classical model that has contributed to the elucidation of mechanisms of axoplasmic flux and neuronal transmission. This neuronal system has also played a critical role in the demonstration of transport, processing and translation of mRNA locally at the pre-synaptic terminal. The questions that now arise are 1) what are …

  Characterization of RNA-binding proteins in presynaptic terminals of squid (Loligo) neurons, AP.R
• 3.0 international workshop on imaging fuction in cells and organisms | ribeirao preto - sp, AO.R

(Only some records are available in English at this moment)

• Abstract

  SummaryDuring my doctoral thesis I identified and partially characterized a novel 65 kDa RNA binding protein (p65) in presynaptic terminals of the Brazilian squid Loligo plei. Based on sequences obtained by mass spectroscopy from purified p65, two polyclonal antibodies raised in rabbits were immunoreactive towards the consensus sequences for RNA binding (the RNA recognition motifs, refer…

  Identify and characterize proteins containing the RNA-binding motifs RNP1 and RNP2 in the presynaptic terminals of neurons from squid photoreceptors, BP.PD

• Abstract

  The giant synapse and axons of squid (Loligo) represent an important classical model that has contributed to detailed mechanisms of axoplasmic flux and neural transmission. This neuronal system has also played a critical role in the long standing question of whether local mRNA processing and protein synthesis occur at the synapse. It is now known for both mammalian and invertebrate system…

  Visiting researcher at the Marine Biological Laboratory - Woods Hole, MA, USA: characterization of a novel 65 kDa RNA-binding protein in presynaptic terminals of squid (Loligo) neurons, BE.PQ