CV Lattes
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Universidade Federal do ABC (UFABC). Centro de Ciências Naturais e Humanas (CCNH) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Graduated in Biomedicin at Universidade Federal de São Paulo (1998), master's at Psychobiology from Universidade Federal de São Paulo (2000) and ph.d. in Science from Universidade Federal de São Paulo (2005). Post-doc in Neuroscience at University of Florida (2016). Nowadays, professor at Federal University of ABC and supervisor at Neuroscience and Cognition programm. Has experience in Pharmacology, acting on the following subjects: psychopharmacology, neurodegenerative diseases, drug addiction, medicinal plants, adaptogens, animal models. (Source: Lattes Curriculum)
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Alzheimer's (AD) and Parkinson's (PD) diseases are some of the most debilitating neurodegenerative pathologies. Sadly, the current pharmacotherapy consists of drugs with limited potential administered to restore relevant neurotransmitter systems, such as acetylcholinesterase inhibitors blocking the enzyme responsible for the metabolizing acetylcholine in AD and L-dopa and other agents tha…
The central nervous system plays a crucial role in coordinating the body's balance, however, natural aging or pathological processes can lead to the accumulation of metabolites contributing to neurodegenerative diseases, characterized mainly by inflammatory processes. In the ethnopharmacological context, yerba mate (Ilex paraguariensis) has emerged as a potential therapeutic intervention,…
Neuroinflammation and oxidative stress are elements present in the vast majority of pathological conditions. Therefore, substances capable of modulating anti-inflammatory and oxidative pathways have been considered as a promising strategy to attenuate these processes and, consequently, reduce symptoms and delay the progression of neurodegenerative diseases and other psychopathologies. In …
Ayahuasca is a psychedelic drink derived from the decoction of the leaves of Psychotria viridis and the vine Banisteriopsis caapi, which provides DMT and ²-carboline alkaloids, respectively, capable ofpromote autonomic and psychotropic effects. In ritualistic and religious contexts, the drink is used regularly and periodically, which is why research has been committed tointervention proto…
Alzheimer's disease is a neurodegenerative disorder responsible for approximately 50-70% of diagnosed dementia cases and directly affects patients' quality of life. Although its pathogenesis is not yet fully understood, a number of metabolic alterations have already been identified as important components in disease progression, including mechanisms of oxidative stress and neuroinflammati…
Ayahusaca is a brew used in ritualistic ceremonies, prepared by decoction of Banisteriopsis caapi e a Psychotria viridis. The leaves of P. viridis possess the hallucinogenic compound DMT while the stem of B. caapi has beta-carboline alkaloids which are monoamine oxidase (MAO) inhibitors. As consequence, the DMT metabolism is inhibited in the gastrointestinal tract allowing the DMT absorpt…
Ayahusaca is a brew used in ritualistic ceremonies, prepared by decoction of Banisteriopsis caapi e a Psychotria viridis. The leaves of P. viridis possess the hallucinogenic compound DMT while the stem of B. caapi has beta-carboline alkaloids which are monoamine oxidase (MAO) inhibitors. As consequence, the DMT metabolism is inhibited in the gastrointestinal tract allowing the DMT absorpt…
Oxidative stress is one of the main features associated with aging and neurodegenerative diseases, leading to a series of disturbances of cell homeostasis, including mitochondrial dysfunction. The Nrf2 pathway is a master regulator of redox homeostasis and compounds that act as inducers of this signaling pathway have been studied as promising therapeutic and prophylactic agents. It is wel…
Ginseng (Panax ginseng) has many protective effects that include treatment of disabilities caused by traumatic brain injury, stroke, multi-infarct dementia, cerebral arteriosclerosis, cerebral edema, inflammation, Alzheimer's disease and vascular dementia related to age . Although many of its reported actions have been attributed to their antioxidant properties, the cellular mechanisms in…
| 1 / 1 | Ongoing grants |
| 1 / 1 | Completed research grants |
| 3 / 3 | Ongoing scholarships in Brazil |
| 5 / 3 | Completed scholarships in Brazil |
| 1 / 1 | Ongoing scholarships abroad |
| 1 / 1 | Completed scholarships abroad |
| 12 / 10 | All research grants and scholarships |
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