CV Lattes
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Universidade de São Paulo (USP). Faculdade de Medicina (FM) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Dr. Titan obtained her MD degree at Faculdade de Medicina, University of São Paulo in 1999, followed by residency in Internal Medicine in 2001 and Nephrology Fellowship in 2003 at the same institution. In 2009, she completed her PhD in Nephrology at the University of São Paulo. She is the principal investigator of the Progredir Cohort in Sao Paulo, Brazil. She is currently nephrologist at the Division of Nephrology and Hypertension at Mayo Clinic, Rochester, Minnesota, United States, and is also professor at the Postgraduate Program of the Nephrology Division of the Hospital das Clínicas, School of Medicine, University of São Paulo. She works with clinical and epidemiological research with a focus on epidemiology, biomarkers and mechanisms of progression of chronic nephropathies of various etiologies (diabetic nephropathy, chronic kidney disease lato sensu, glomerulopathies), as well as complications related to CKD, such as cardiovascular risk and minera-bone metabolism disorders. (Source: Lattes Curriculum)
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The role of urinary retinol-binding protein (RBP) as a biomarker of CKD in proximal tubular diseases, glomerulopathies and in transplantation is well established. However, whether urinary RBP is also a biomarker of renal damage and CKD progression in general CKD is not known. In this study, we evaluated the association of urinary RBP with renal function and cardiovascular risk factors in …
Lupus nephritis (LN) is a frequent complication with high morbidity and mortality. Chronic kidney disease (CKD) is observed in 8 to 15% of the patients after 5 years of follow up. LN is an inflammatory disorder related to a systemic autoimmune activation. Once inflammation is shutdown, several renal and nonrenal factors such as residual proteinuria, hypertension and ethnicity of the patie…
Chronic kidney disease has become an important Public Health issue in most developed and developing countries, with increasing incidence and prevalence rates. The cost associated with chronic kidney disease patients is very high, derived from renal replacement therapy and the cost associated with the high cardiovascular risk of this population. Primary and secondary preventive measures ar…
In the last years, albuminuria has emerged as an important biomarker of CKD progression, risk of ESRD, cardiovascular disease and mortality. In the context of proteinuric renal diseases, albuminuria is largely used to assess risk of CKD progression and response to medical treatments. However, it is currently known that in a subgroup of CKD patients, albuminuria does not present a good per…
Chronic kidney disease (CKD) is a growing public health problem, as well as the number of patients requiring renal replacement therapy, is an independent risk factor for cardiovascular diseases. The cost associated with the treatment reaches about 10% of the NHS budget. Preventive actions are imperative, and it is necessary to better understand the mechanisms involved in the progression o…
CKD has become a major health problem worldwide. The morbidity and mortality related to CKD is very high, and the costs associated with this condition are increasing. Despite this reality, we have few biomarkers of this disease, resulting in limitations regarding our ability in diagnosis, prognosis and treatment of CKD. The search for new biomarkers of renal function and uremia is intense…
| 3 / 3 | Completed research grants |
| 6 / 2 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 10 / 6 | All research grants and scholarships |
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