Abstract
Multiple endocrine neoplasias (MENs) are tumoral familial syndromes which involve several endocrine glands (pituitary, parathyroids, thyroid, endocrine pancreas and adrenal). Patients with MEN type 1 (MEN1) usually carry inactivating mutations in the MEN1 gene, while patients with MEN type 2 (MEN2) usually carry activating mutations in the RET proto-oncogene. Recently, patients with MENs …