Abstract
Phospholipases A2 (PLA2s, EC 3.1.1.4) specifically catalyze the hydrolysis of the sn-2 acid-ester bonds of glycerophospholipids liberating, as product of the catalysis, fatty acid and lysophospholipids. They are found in plants, mammals and in venom of vertebrate and invertebrate animals and are involved in a wide variety of physiological processes. Human secreted phospholipase A2 of the …