CV Lattes
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Universidade de São Paulo (USP). Faculdade de Ciências Farmacêuticas de Ribeirão Preto (FCFRP) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduate at Odontology from Universidade Federal de Uberlândia (1999), master's at Immunology from Universidade Federal de Uberlândia (2003) and ph.d. at Applied Imunology from Universidade de São Paulo (2006). Has experience in Immunology, focusing on Celular Imunology, acting on the following subjects: cytokines, chemokines, fatty acids, peanut and ibd. (Source: Lattes Curriculum)
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This project aims to modernize the infrastructure of the General Animal Facility (also known as the Central Animal Facility) of the USP Campus Administration in Ribeirão Preto (PUSP-RP). This is a multi-user unit essential for the production and supply of rodents (mice and rats) within the USP Animal Facility Network. The animals are produced under high sanitary and genetic standards, ser…
An increasing number of sequelae and people suffering from the long-term debilitating effects of COVID-19 (long COVID-19 or post-acute COVID-19 syndrome - PACS) highlight the necessity of special attention to the interactions between SARS-CoV-2 and other organs such as intestine which, in addition to the lungs, are affected by the virus. Gastrointestinal (GI) symptoms such as abdominal pa…
An increasing number of sequelae and people suffering from the long-term debilitating effects of COVID-19 (long COVID-19 or post-acute COVID-19 syndrome - PACS) highlight the necessity of special attention to the interactions between SARS-CoV-2 and other organs such as intestine which, in addition to the lungs, are affected by the virus. Gastrointestinal (GI) symptoms such as abdominal pa…
The current therapeutic options for Inflammatory Bowel Diseases (IBD) are limited. Even using common anti-inflammatory, immunosuppressive or biological therapies, many patients become unresponsive to the treatments, immunosuppressed or unable to restrain secondary infections. Statins are cholesterol-lowering drugs with non-canonical anti-inflammatory properties, whose underlying mechanism…
COVID-19 is an infectious disease caused by the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), and according to the World Health Organization (WHO), to date, SARS-CoV-2 has already infected more than 86.4 million people worldwide with 1,884,341 deaths. This virus affects mainly the respiratory system, but the gastrointestinal tract (GIT) is also a target, meanwhile SARS-CoV…
Anti-TNF monoclonal antibodies are commonly used in IBD treatment. However, some patients are not responsive to this therapy and the concomitant use of this biologics with other immunosuppressive drugs that ameliorate treatment leads to important adverse effects. On the other hand, the levels of the hormone dehydroepiandrosterone (DHEA) are reduced in CD and UC patients, while the supplem…
(Only some records are available in English at this moment)
SARS-CoV-2 infection has been associated with persistent clinical symptoms, including gastrointestinal manifestations, as well as alterations in the composition of the intestinal microbiota. These factors may be related to COVID-19 severity and may contribute to increased intestinal inflammation in susceptible individuals. In this context, the mechanisms underlying the interaction between…
COVID-19 remains a major concern for the global scientific community. The sequelae of SARS-CoV-2 infection, collectively referred to as "long COVID" or "post-acute COVID-19 syndrome (PACS)," affect multiple organ systems, including the respiratory and gastrointestinal tracts.Gastrointestinal manifestations are observed in both acute and long COVID, commonly presenting asdiarrhea, abdomina…
The COVID-19 pandemic has affected millions of people worldwide, leading to a myriad of clinical manifestations and disease worsening, especially in older non-vaccinated patients, from male sex, an in those presenting comorbidities such as diabetes. In acute disease, gastrointestinal (GI) symptoms can be present and also persist in the convalescence phase, together with other sequelae pos…
(Only some records are available in English at this moment)
The interaction between pre-existing intestinal inflammation and gut health is a topic of growing interest, especially regarding potential sex-specific differences. This undergraduate research activity aims to investigate the impact of colitis and its differences in the intestines of male and female mice. The study will use dextran sulfate sodium (DSS) to induce colitis and examine whethe…
The Human Immunodeficiency Virus (HIV), the cause of Acquired Immunodeficiency Syndrome (AIDS), is considered a major public health problem worldwide. By 2017, in Brazil, it is estimated that 867 thousand people living with HIV. Although there is the treatment for HIV infection, HIV + patients even on antiretroviral therapy have a constant activation of the innate and adaptive immune syst…
A solicitação desta bolsa de Treinamento Técnico vinculada ao projeto "EFEITO IMUNOMODULADOR DE DEHIDROEPIANDROSTERONA (DHEA) NA RESPOSTA IMUNE DE PACIENTES COM DOENÇA DE CROHN NÃO RESPONSIVOS À TERAPIA COM ANTI-TNF-±" baseia-se na necessidade de auxílio técnico especializado para execução do plano de trabalho, além de propiciar o treinamento de estudante de nível superior. A colite ulcer…
(Only some records are available in English at this moment)