CV Lattes
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Universidade de São Paulo (USP). Faculdade de Medicina de Ribeirão Preto (FMRP) (Institutional affiliation from the last research proposal) Birthplace: Brazil
bachelor's at Medicina from Universidade de São Paulo (1974), bachelor's at Ciências Biologicas from Universidade de São Paulo (1970), master's at Biochemistry from Universidade de São Paulo (1978) and doctorate at Biochemistry from Universidade de São Paulo (1983). Has experience in Biochemistry, focusing on Molecular Biology, acting on the following subjects: 'schistosoma mansoni', schistosoma mansoni, schistosoma mansoni, proteassoma and proteasome. (Source: Lattes Curriculum)
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This research project seeks to analyze the effects of some substances in the oviposition and the involvement of the same in the signaling pathways of oogenesis the parasite Schistosoma mansoni. For this, the reproductive system and thus egg production in vitro by parasite couples will be analyzed in the presence of deubiquitinating enzymes inhibitors (DUBs) (b-AP15 and PR-619), CNT-siRNA …
Schistosomiasis remains a severe health public problem in several developing countries. Uncountable reports show an increasing emergence of Schistosoma mansoni strains resistant to Praziquantel, the current drug of choice to the Schistosomiasis treatment. In this way, the development of new and efficient drugs against this parasitosis is indispensable. The effect of proteasome inhibitors,…
For decades, studies that evaluate the complexity and immunogenicity of the tegument of Schistosoma mansoni has been conducted. This is because the membrane antigens associated with the surface on the tegument of S. mansoni have a great potential in vaccine development because they are exposed to the host immune system, but also are of great importance in biological studies of host-parasi…
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