CV Lattes
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Universidade Estadual de Campinas (UNICAMP). Instituto de Biologia (IB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Bachelor's at Ciências Biológicas from Universidade de São Paulo (2003) and doctorate at Biochemistry from Universidade de São Paulo (2008). Has experience in Biochemistry and Molecular Biology of Microorganisms, acting on the following subjects: regulation of gene expression and stress response. (Source: Lattes Curriculum)
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Bacterial genetic material is organized into a compact structure, the nucleoid. Several proteins associate with the nucleoid and cause changes in its structure and gene expression. The study of these proteins has been carried out in bacteria with genomes of low A+T content, and several preferentially bind to regions where the A+T content is higher than the mean value of the genome. This r…
Histone-like nucleoid structuring proteins (H-NS) are DNA-binding proteins with critical roles in chromosome organization and global gene expression regulation in bacteria. Post-translational modifications (PTM) have been recently identified in H-NS proteins in Enterobacteriaceae and other gamma-proteobacteria, suggesting the involvement of PTM in the regulation of H-NS proteins. The beta…
Studies on proteins that organize the genetic material and, consequently, affect gene expression, are still limited to just a few bacteria. In the case of the H-NS protein, which bridges segments of the chromosome, the studies focus on the gamma-proteobacteria Escherichia coli and Salmonella enterica. In alpha- and beta-proteobacteria, H-NS proteins are naturally shortened in several regi…
Bacterial DNA is organized into a compact structure, the nucleoid. Several proteins associate with the nucleoid and cause changes in its structure and gene expression. These proteins have been mainly studied in bacteria with genomes of low A+T content, and several of them preferentially bind to regions where the A+T content is higher than the mean value of the genome. This research propos…
Bacterial DNA is organized into a compact structure, the nucleoid. Several proteins associate with the nucleoid and cause changes in its structure and gene expression. These proteins have been mainly studied in bacteria with genomes of low A+T content, and several of them preferentially bind to regions where the A+T content is higher than the mean value of the genome. This research propos…
The structuring of the genetic material of bacterial cells differs from the process known in eukaryotes. As a consequence, the bacterial process can be an effective target for the development of antibacterial drugs. The H-NS protein (histone-like nucleoid structuring) is recognized by its role in the nucleoid structure of Escherichia coli and Salmonella enterica. In addition, H-NS also si…
(Only some records are available in English at this moment)
| 1 / 1 | Ongoing grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 8 / 5 | Completed scholarships in Brazil |
| 12 / 9 | All research grants and scholarships |
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