CV Lattes
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Universidade Federal de São Carlos (UFSCAR). Centro de Ciências Biológicas e da Saúde (CCBS) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Assistant professor at Federal University of São Carlos (UFSCar). The overall research goal is to understand determinant features of embryonic development and pregnancy success. Much of the current effort is to elucidate cellular and molecular mechanisms involved in embryonic competence for the establishment of technologies that optimize the application of the embryo in the reproductive management. (Source: Lattes Curriculum)
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The pathways and biological processes associated with embryo competence, cryosurvival and the success of obtaining an embryo-derived pregnancy are still lacking. The present work aims to elucidate strategies and understand the mechanisms of the competence of in vitro produced (IVP) bovine embryos in a holistic approach. In a series of three experiments, we will look for: 1) identify diffe…
The pathways and biological processes associated with embryo competence, cryosurvival and the success of obtaining an embryo-derived pregnancy are still lacking. The present work aims to elucidate strategies and understand the mechanisms of the competence of in vitro produced (IVP) bovine embryos in a holistic approach. In a series of three experiments, we will look for: 1) identify diffe…
The eukaryotic translation elongation factor 1A1 (eEF1A1) is a protein expressed during the embryonic phase that acts in processes such as embryogenesis and proliferation of the cell cycle, however, an association between this expression and the oxidative stress and apoptosis pathways has already been reported. Therefore, this study aims to evaluate the effect of attenuation and indirect …
The pathways and biological processes associated with embryo competence, cryosurvival and the success of obtaining an embryo-derived pregnancy are still lacking. The present work aims to elucidate strategies and understand the mechanisms of the competence of In Vitro Produced (IVP) bovine embryos in a holistic approach. In a series of three experiments, we will look for: 1) identify diffe…
Cryopreservation is a technology of commercial application which aims to solve problems associated to surplus In Vivo or In Vitro Produced embryos (IVP) storage, allowing the delay for the convenient moment to transfer to the recipients. However, IVP embryos are known for their low cryopreservation capacity, since they have shown an increased sensitivity to refrigeration when compared to …
To ensure the proper functioning of a cell, precise regulation of gene expression is required. In this context, the transcription factor NF-kB is involved in various biological processes, responding to pro-inflammatory cytokine stimuli such as tumor necrosis factor-alpha (TNF-±), and regulating the expression of genes related to immune responses, inflammation, and cell survival. While wel…
This present work aims to analyze and investigate the potential relationships between the technique of cryopreservation in in vitro produced bovine embryos and the cellular and nuclear damage inflicted on the embryos, such as nuclear condensation, nuclear fragmentation, and apoptosis. The investigations will be conducted through image analysis, utilizing the nuclear morphometry technique.…
Originally mainly identified for their immunoregulatory activities, cytokines are recognized as key regulators in cell differentiation processes. Thus, several studies have been developed with the aim of elucidating the activities of these proteins in numerous procedures, including folliculogenesis and ovulation processes. However, given the pleiotropic nature of cytokines, the characteri…
(Only some records are available in English at this moment)
The proposal objectives are: Experiment I - Study the effect of subspecies (Bos taurus indicus vs. Bos taurus taurus), different embryo culture media (SOFaa + 2.5% FCS versus SOFaa + 2.5% FCS + 0.3 µM PES) and embryo condition (fresh versus vitrified) on global gene expression pattern (microarray) cryotolerance, lipid content (Sudan Black), and lipid fingerprint mass spectrometry profile …
| 2 / 2 | Ongoing grants |
| 1 / 0 | Completed research grants |
| 3 / 3 | Ongoing scholarships in Brazil |
| 10 / 6 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 17 / 12 | All research grants and scholarships |
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