Jefferson Russo Victor

• Abstract

  Although used for therapeutic purposes in various pathological processes with immunological etiology for many years, the precise mechanisms by which IgG antibodies can modulate immunity in the absence of antigen are not known, especially when considering their possible role in primary lymphoid organs such as the thymus. In recent years, several studies have shown that IgG can effectively …

  The Hooks without bait theory: mechanisms involved in the immunomodulatory effect of IgG on the thymic modulation of TCD4, TCD8, gdT, iNKT MAIT and B cells, focus on atopic diseases and COVID-19, AP.JP

• Abstract

  IgG antibodies from allergen-tolerant mice can modulate the activation of B lymphocytes and the production of cytokines by peripheral T lymphocytes in vivo. They can induce the differentiation of peripheral regulatory B lymphocytes, producing IL-10 (B10), which exerts an inhibitory role in developing allergic lung inflammation. Furthermore, it has also been demonstrated that these antibod…

  Pilot study on cellular events involved in the immunomodulatory effect of murine IgG antibodies on thymic differentiation of TCD4, TCD8, gamma-deltaT, and B cells, BP.IC

• Abstract

  Among the evidence that gave rise to the hypothesis of this project, it has been demonstrated that the IgG from atopic (allergic) individuals is capable of inhibiting thymic maturation of IFN-³-producing CD4 T lymphocytes, which play an inhibitory role in the development of allergies (1). In the same context, it has been shown that IgG from atopic individuals can promote the maturation of…

  Elucidation of the cellular and molecular events involved in the immunomodulatory effect of IgG antibodies on the thymic differentiation of Tgd lymphocytes with a focus on atopic diseases and COVID-19, BP.MS

• Abstract

  Although used for therapeutic purposes in several pathological processes, the precise mechanisms by which IgG antibodies can modulate immunity in the absence of antigen are not known. In recent years, several studies have shown that IgG antibodies can differentially play an immunomodulatory role on peripheral human T lymphocytes or on primary lymphoid organs such as the thymus. This effec…

  Elucidation of cellular and molecular events involved in the effect immunomodulator of IgG antibodies on the thymic differentiation of TCD4 lymphocytes and TCD8 focusing on atopic diseases, BP.DD

(Only some records are available in English at this moment)

• Abstract

  Atopic Dermatitis (AD), also referred to as Atopic Eczema, affects approximately 10% of the population, primarily manifesting in childhood but often persisting into adulthood. While its exact etiology remains elusive, a combination of genetic predisposition, compromised skin barriers, and immune dysregulation is implicated. AD significantly diminishes quality of life and frequently co-occ…

  Phenotypic characteristics and functional aspects of exhausted T cells in patients with Atopic Dermatitis and their relationship with disease severity., BE.EP.DD