CV Lattes
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Universidade Federal do ABC (UFABC). Centro de Ciências Naturais e Humanas (CCNH) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduation at Bacharelado em Ciências Biomédicas from Universidade Estadual de Campinas (2004), graduation at Bacharelado e Licenciatura em Ciências Moleculares from Universidade Estadual de Campinas (2005), master's at Cancerology from Fundação Antônio Prudente (2008) and doctorate at Cancerology from Fundação Antônio Prudente (2012). Has experience in Genetics, acting on the following subjects: câncer, colorretal, hereditário, tp53 and genética. (Source: Lattes Curriculum)
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TP53 gene is located in the short arm of the chromosome 17 and encodes a protein that prevents cells from accumulating DNA damage by induction of pathways leading to cell arrest or apoptosis. TP53 mutations are found in approximately 50% of human cancers. While most of tumor suppressor genes are inactivated by mutation leading to absence of protein synthesis, more than 80% of TP53 alterat…
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