Abstract
The purine nucleotides, as ATP and pyrimidine, as UTP, are stored together with noradrenaline in synaptic vesicles, being released in nerve terminals. Their action is mediated by purinergic receptors P1 and P2, expressed in various tissues. The purinergic system is known to be involved in cardiovascular regulation. Both nucleotides stimulate vasoconstriction and dilatation, growing of vas…