Abstract
Cardiac remodeling (CR) occurs in response to certain types of aggression, such as pressure overload, and it can be clinically manifested by changes in size, shape and function of the heart. In the model of supravalvar aortic stenosis (SVAS) in rats, echocardiographic studies have shown that, after 2 and 6 weeks of SVAS induction, rats develop left ventricular hypertrophy, diastolic dysfu…