CV Lattes
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Fundação Antonio Prudente (FAP). A C Camargo Cancer Center (Institutional affiliation from the last research proposal) Birthplace: Brazil
I hold a Bachelor's degree in Biological Sciences from São Paulo State University (UNESP) - Botucatu, a PhD in Bioinformatics from the Institute of Mathematics and Statistics (IME) - University of São Paulo (USP), and I completed a postdoctoral fellowship at A.C.Camargo Cancer Center. Currently, I am a researcher at the Cancer Institute of the State of São Paulo (ICESP) and the Hospital das Clínicas of the Faculty of Medicine at USP. My research focuses on systems biology and bioinformatics, with an emphasis on mechanisms of multidimensional data integration, computational modeling, and the application of artificial intelligence in cancer. (Source: Lattes Curriculum)
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Colon cancer is a leading cause of cancer death worldwide. Although the survival of patients with metastatic disease has improved with the use of systemic therapy, many of them develop primary resistance with progression within a few months. Despite the genomic characterization of these tumors has positively influenced the therapy offered, it is still a challenge to identify alterations t…
Colon cancer is a leading cause of cancer death worldwide and approximately 50% of patients develop liver metastases during the course of the disease. Although surgical resection provides a 5-year survival rate around 40%, most patients have non-resectable disease at diagnosis. In this case, the scenario is devastating due to the resistance of tumor cells to standard treatment with chemot…
High-grade serous carcinoma (HGSC), the most prevalent histological type of ovarian cancer, has the lowest survival rates and is the leading cause in the world of gynecological cancer-related deaths. HGSC is characterized by the high frequency of mutations in the TP53 gene, genomic instability and few actionable targets for therapy. Despite an initial clinical response in most patients, r…
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