Abstract
The communication between the oocyte and surrounding somatic cells is essential for the differentiation of the cumulus-oocyte complex (COC). Oocyte secreted factors (OSFs), including fibroblast growth factors (FGF) and bone morphogenetic protein 15 (BMP-15), are important mediators in the communication between the oocyte and cumulus cells. FGF10 is expressed in the oocyte and its receptor…