Abstract
Nuclear factor-kB ( NF-kB) is a family of highly regulated dimeric transcription factors that activate classical and alternative pathways. Classical is the major one involved, in different cell types, in the response to inflammatory stimuli originated from cytokines such as tumor necrosis factor-a (TNF-a), interleukin 1 (IL-1), and pathogen-associated molecular patterns (PAMPs). The alter…