Abstract
Invasive aspergillosis (IA) is major cause of morbidity and mortality in profoundly immunocompromised patients. Although many species of Aspergillus have been isolated in nature, A. fumigatus is the primary causative agent of human infections. Once the conidia reach the alveoli, they germinate and produce hyphae that invade the pulmonary tissue. These hyphae have a tropism for blood ves…