Ana Paula Pereira Velosa

• Abstract

  Type V collagen (Col V) has immunogenic and antigenic features and potential to become an autoantigen in various pathologies, when exposed to the immune system. Studies have shown an increase in the frequency of anti-Col V antibodies in the serum of patients in the early stages of systemic sclerosis (SSc), a chronic disease characterized by fibrosis of the skin and internal organs, such a…

  Effect of induction of tolerance with immunogenic peptides of collagen type V on pulmonary fibrosis associated with experimental systemic sclerosis, AP.R
• 31st European Congress of Pathology, AR.EXT

• Abstract

  Collagen type V (COLV) has immunogenic and antigenic properties, and potential to become an autoantigen in several pathologies when exposed to the immune system. Our group has described an experimental model of systemic sclerosis (SSc) induced in rabbits immunized with COLV who develop skin and lung fibrosis, immune and vascular changes similar to the disease in humans. Recent works carri…

  EVALUATION OF ANTIGENIC POTENTIAL OF THE COLLAGEN TYPE V IN SYSTEMIC SCLEROSIS, AP.R

(Only some records are available in English at this moment)

• STUDY OF TOLERANCE MECHANISMS INDUCED BY ORAL ADMINISTRATION OF IMMUNOGENIC COLLAGEN V PEPTIDES IN A MODEL OF SYSTEMIC SCLEROSIS., BP.TT

• Abstract

  Systemic sclerosis (SSc) is a rheumatic autoimmune disease of unknown etiology, characterized mainly by vasculopathy, autoimmunity and fibrosis of the skin and internal organs. The accumulation of collagen fibers is the most prominent feature in SSc pathogenesis, with the increase in the expression of type V collagen (Col V), already in the early stages of the disease. In recent years, Co…

  Biochemical fractionation and evaluation of immunogenicity of collagen V in systemic sclerosis, BP.IC