Beatriz Stein Neto in research grants and scholarships supported by FAPESP.
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Aldehyde dehydrogenese-2 (ALDH-2) is a mithocondrial enzyme which metabolizes reactive aldehydes. Aldehydes accumulation such as 4-hidroxinonenal (4-HNE) has been related to increased pain. 4-HNE is an aldehyde formed by the oxidation of unsatured lipids in the mitochondrial membrane. Recently, our group showed that activation of ALDH2, using a small molecule called Alda-1, displays antin…
Aldehyde-dehydrogenase 2 (ALDH-2) is a mitochondrial enzyme responsible for the metabolism of toxic aldehydes, including the removal of 4-hydroxynonenal (4-HNE), an aldehyde generated during mitochondrial lipid peroxidation. 4-HNE accumulation has been recently related to increased pain. Recent data from our group has been shown that activation of ALDH2, using a small molecule (Alda-1), d…
| 2 / 2 | Completed scholarships in Brazil |
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