CV Lattes
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Universidade de São Paulo (USP). Faculdade de Zootecnia e Engenharia de Alimentos (FZEA) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Bachelor of Biological Sciences from the Federal University of Pará (UFPA), Master in Cell Biology also from UFPA. PhD in Sciences by the Faculty of Veterinary Medicine and Animal Science (FMVZ), University of São Paulo (USP). Part of his doctoral research project was carried out at the University of Guelph (Ontario, Canada). In 2015, started a Post-Doctorate at the Faculty of Animal Science and Food Engineering (FZEA) at USP. Part of this project was carried out at the University of California Davis (USA) during 1 year from 2016 to 2017. Works currently as a Postdoc at the University of Montreal (Quebec, Canada). Has experience in Epigenetics; Embryology; In vitro Embryo Production: Somatic Cell Nuclear Transfer and In Vitro Fertilization; Cytology: Adult and Embryonic stem cells; Molecular biology. (Source: Lattes Curriculum)
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The persistence of somatic epigenetic memory is indicated as the main barrier for an efficient nuclear reprogramming. Reproductive technologies like somatic cell nuclear transfer (SCNT) are influenced by this memory. In mice H3K9 hypermethylation on somatic nuclei has been show as the major regulator of epigenetic memory. However, little is known in bovine. Based on that, we hypothesized …
The nuclear reprogramming of somatic cell to an embryonic state has several applications, such as basic research in developmental biology, cell therapy in medicine, genetic improvement of livestock animals and species conservation. The two principal techniques used to achieve nuclear reprogramming are Somatic Cell Nuclear Transfer (SCNT) and Induced Pluripotent Stem Cell (iPS). There are …
Epigenetic mechanisms are responsible for many cellular functions. Amongst them, is the epigenetic memory maintained during cell division. Consolidation of this information is made by stable chemical marks as DNA methylation and histone modification. Understanding epigenetic mechanism allows the development of several studies, such as nuclear reprogramming, which is directly influenced by…
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