Abstract
It is known that the transition from normal mucosa to invasive carcinoma is a complex, multistep and multifactorial etiology, where Potentially Malignant Lesions (PML) has a great relevance. The oral leukoplakia (OL) is the most representative of the PML. The dysplasia is considered as highest risk factor for malignant transformation of OL, but the padronization and reproducibility of gra…